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KMID : 0614619930250040782
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Korean Journal of Gastroenterology
1993 Volume.25 No. 4 p.782 ~ p.787
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A Case of Hepatocellular Carcinoma within an Atypical Adenomatous Hyperplastic Nodule in a cirrhotic Liver
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한병근
장우익/이용규/이동기/권상옥/심영학/조미연/노병선
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Abstract
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Adenomatous hyperplasia (AH), defined as a sizable parenchymal nodules that may follow acute or chronic liver injury, has been reported as precursor lesion of hepatocellular carcinoma in the cirrhotic liver. These lesions often coexist with
obvious
malignant foci as small nodule-in-nodule. Morphologically AII can be divided into 'ordinary' and 'atypical (AAH)' types. The former consisted of hepatocytes similar to those of the surrounding liver. The latter type was composed of hepatocytes
showing
nuclear, cellular and structural atypia relative to the surrounding liver, and showed irregular or sparse portal tracts. Cytological and structural patterns are characteristically heterogenous within a nodule. Now AAH are considered to be
precancerous
lesion evolving to early hepatocellular carcinoma.
Authors report one case of hepatocellular carcinoma within an atypical adenomatous hyperplastic nodule in 55-year-old male with a review of literatures.
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